Effect of Indigofera tinctoria on ?-amyloid (25-35) mediated Alzheimer’s disease in mice: Relationship to antioxidant activity
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چکیده
منابع مشابه
Varenicline Ameliorates Learning and Memory Deficits in Amyloid β(25–35) Rat Model of Alzheimer’s Disease
Introduction: Alzheimer’s disease (AD) is a enfeeble neurodegenerative disorder characterized by increased β-amyloid (Aβ) deposition and neuronal dysfunction leading to impaired learning and recall. Among proposed risk factors, impaired cholinergic transmission is a main cause for incidence of disease. Methods: In the present study, effects of the intracerebroventricularly administration of an ...
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AIM Gastrointestinal (GI) nematodes are considered as a major constraint for successful sheep production. Control of these parasites heavily relies on the use of chemical anthelmintics. Over the past decades, the development of anthelmintic resistance to various groups of anthelmintics and problem of drug residues in animal products has awakened interest in medicinal plants as an alternative so...
متن کاملAntidepressant and Nootropic Activity of Aqueous Extract of Indigofera Tinctoria in Mice
Objective: The present study was undertaken to evaluate the antidepressant and nootropic potential of aqueous extract of Indigofera tinctoria (ITAE). Methods: Antidepressant activity of ITAE was evaluated in mice by using the forced swim test (FST), tail suspension test tail suspension test and tetrabenazine induced catalepsy and ptosis models at doses of 250 and 500 mg/kg orally. Nootropic act...
متن کاملRosmarinic acid mitigates learning and memory disturbances in amyloid β(25–35)-induced model of Alzheimer’s disease in rat
Abstract Background and Objective: Alzheimer’s disease (AD) is a weakening neurodegenerative disorder typified by increased b-amyloid (Ab) deposition and neuronal dysfunction causing to impaired learning and memory. Among proposed risk factors, induced oxidative stress is a main cause for incidence of the disease. The aim of this study was to determine the effects of the rosmarinic acid on lear...
متن کاملPhytochemical Investivations of Indigofera Tinctoria Linn Leaves
Studies of Indigofera tinctoria Linn has shows that it possesses low toxicity. Phytochemical evaluation of leaf extract of Indigofera tinctoria Linn has been carried out to characterize some constituents present therein. Qualitative analysis of the extracts showed the presence of flavonoids, alkaloids, glycosides, terpenoids. Five compounds have been isolated from petroleum ether extract and me...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2010
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v5i1.5644